Frovatriptán se utiliza para tratar los síntomas de los dolores de cabeza por migraña (dolores de cabeza intensos y punzantes que algunas. La cabergolina se usa para tratar la hiperprolactinemia (niveles altos de prolactina, una sustancia natural que ayuda a las mujeres que están. Naratriptán se utiliza para tratar los síntomas de los dolores de cabeza por migraña (dolores de cabeza intensos y punzantes que algunas.

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Sumatriptan in pod practice: Sumatriptan for migraine attacks in children: The main pharmacological effects of ergotamine are: Arteriographic findings consist of arterial spasm, collateral network and in situ thrombosis. Despite the multiple symptoms of ergotism, peripheral ischemia secondary to vasospasm is the most frequent and it affects 0.

Musikatavorn K, Suteparuk S.

Cabergolina: MedlinePlus medicinas

Treatment duration depends on individual progress of each patient and, in case of persistent vasospasm, the possibility that the patient is still using ergotamine derivatives for migraine attacks should be investigated.

Introduction During the Middle Ages the first descriptions of intoxication caused by ergotamine derivatives were made.

Its active components are alkaloids, all derived from lysergic acid. Rua Estela,bloco E, conj. There was no previous history of smoking, heart disease or intermittent claudication, but eergotamina patient reported a history of migraine with chronic use of ergotamine tartrate. After drugs were suspended and anticoagulants, vasodilators and antiplatelet drugs were prescribed, the patient progressed with improvement of pain, paresthesia and return of normal skin color and distal pulses in lower limbs.

No conflicts of interest declared concerning the publication of this article. Acute arterial occlusion caused by ergotamine derivatives.

The patient progressed with improvement of pain and upper and lower limb paresthesia, return of normal skin color and of distal pulses in the lower limbs; she was discharged on the sixth hospital day. Ergotamine was discontinued, as well as the use of heparin, cilostazol and buflomedil. Ergktamina unresponsive to multiple therapeutic modalities, including sodium nitroprusside, resulting in limb loss.


Edison Barreto de Souza Av. Prostaglandins, ergot, alkaloids and other drugs.

Intranasal sumatriptan for the acute treatment of migraine in children. In recent publications, percutaneous angioplasty has been reported as an adjuvant treatment for arterial spasm; however, due to the risk of injury to the intimal ergotamnia of the vessels, consequently causing thrombosis, it should be avoided whenever possible.

Differential diagnosis is necessary, since occlusive atherosclerotic disease, intoxicacioh disease, arteritides, fibromuscular dysplasia and the Raynaud’s phenomenon all have vasospastic symptoms similar to those of ergotism. Ueberall MA, Wenzel D. Ergotamine derivatives include several drugs widely used in the treatment of acute migraine attacks. Iatrogenic arterial aneurysm associated with ergotamine therapy. Pregnancy outcomes following first trimester exposure to sumatriptan.

Arch Intern Med ; Leung M, Ong M. At examination, she presented with loss of muscular strength on upper limbs, intense pain in lower limbs, below the knee, cyanosis of the toes and absence of distal pulses.

The first ihtoxicacion most important step in the treatment is to discontinue the causing agent; however, vasodilating therapy is fundamental for the improvement of the patient’s clinical status.

Estos casos suelen ser muy raros, teniendo lugar preferentemente en pacientes con enfermedad arterial coronaria o en intoxicacuon que han sido tratados con ergotamina en las 24 horas anteriores. How to cite this article. On the one hand, ergotamine derivatives may damage the vascular endothelium by inducing the proliferation of arterial muscle cells due to stimulation of the platelet-derived growth factor and, on the other hand, they cause thrombosis and necrosis of the tunica media; these are symptoms associated with poisoning by ergotamine.

The fast absorption of the drug and the prolonged effects on the arterial network suggest that both the tight binding to its receptor and the presence of active metabolites in the blood circulation prolong its vasoconstrictor effect. Lack of an interaction between sumatriptan and selective serotonin reuptake inhibitors.


All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License. Despite the fact that the treatment has been adopted empirically and with varying results, it is fundamental to discontinue ergotamine immediately.


Manuscript received Mar 22,accepted for publication Jun 4, By that time, strange epidemics with the characteristic symptom of limb gangrene were reported.

She underwent arteriography, which showed both lower limbs with: Si a las 2 horas no se ha obtenido una respuesta satisfactoria, puede administrarse una segunda dosis de mg.

Ischemic colitis and sumatriptan use.

A year-old female patient was admitted with a sudden onset of paresthesia in upper and lower limbs with 4 days of evolution. Treatment of juvenile migraine with subcutaneous sumatriptan. Ergotism with ischemia in all four extremities: Vascular spasm and gangrene during heparin-dihydro-ergotamine prophylaxis.

Services on Demand Journal. When arterial spasm is observed, especially if it is bilateral and symmetrical, intoxication by ergotamine should be suspected. Do children with migraine respond to oral sumatriptan differently from adults? Despite the fact that acute arterial occlusion caused by ergotamine derivative is a rare clinical condition, it should be considered in the differential diagnosis of ischemic syndromes, especially in young patients without cardiovascular risk factor, or of severe arterial embolism.

Efficacy of subcutaneous sumatriptan in repeated episodes of migraine. Despite nitroprusside being considered an antidote for ergotism due to its efficient action over the vascular smooth muscle, it is used only for severe cases because of problems with dosage, need for an infusion pump and multiple side effects.