The present study was undertaken to test the chemopreventive effects of one herbal medicinal plant, Indigofera aspalathoides, on chemically. The treatment by I. aspalathoides on fibrosarcoma bearing rats has improved the levels Indigofera aspalathoides (I. aspalathoides) treatment for rat arthritis is. Abstract: Civarvembu/ Sivanimba is botanically equated to Indigofera aspalathoides Vahl ex. DC. (Leguminosae). The plant is prescribed for eczema, psoriasis.

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Group I served as normal control, Group II served as fibrosarcoma-induced animals, Group III were fibrosarcoma-bearing animals treated with aqueous extracts of Indigofera aspalathoidesand Group IV animals, which were normal healthy animals treated with Indigofera aspalathoides aqueous extract, served as drug control set.

Indigofera aspalathoides

After the treatment with I. The leaf is trifoliate, pale green, obanceolate, digitate, sessile and crowded on the young branches, stipules minute. The portal will be unavailable all day on Sunday 23rd Dec for maintenance.

It has been suggested that compounds that possess inhibitory effects on cell proliferation and as antioxidants, are considered to be good chemo preventive agents. Antitumor activity of some plants from Meghalaya and Mizoram against murine ascites Dolton’s lymphoma. asplathoides

The body weight progressively declined in tumor hosts and by contrast it increased regularly in controls. The tubes were shaken well. The altered activities of ALT and AST in indigorera serum of fibrosarcoma bearing animals were brought to near normal levels after treatment with the plant extract.


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There was no such change observed in poly herbal formulation treated group of animals. If the animal survived, four additional animals were dosed sequentially so that five animals could be tested.

The whole plant is an ingredient in Civanar vembut tailam and civanar vembut kulit tailam which are popular for skin diseases. The liver is an important site of protein metabolism and it has the highest rate of protein synthesis. Research Journal of Medicinal Plant.

Some reports of its anticancer and antioxidant properties are already been studied by us [ 13 — 16 ]. Govind P, Madhuri S. Results of a clinicohistopathologic correlation in a series of cases.

Echitamine chloride, a plant alkaloid has been reported to inhibit tumor growth as compared to untreated tumor [24]. Indigofeera levels of antioxidant enzymes CAT, SOD and GPx, were corrected to near normalcy in fibrosarcoma-bearing animals by treating with aqueous extract of Indigofera aspalathoides.

Early development of protein metabolic perturbations in the liver and skeletal muscle of tumour-bearing rats. The timestamp is only as accurate as the clock in the camera, and it may be completely wrong. Inhibitory effects of Indigofera aspalathoides on methylcholanthrene-induced chemical carcinogenesis in aspalathoidea. However, if three animals died, the limit test was terminated and the main test was performed.

The filtrate was again concentrated in a China dish and dried in vacuum. The activity levels of nucleic acids such as total DNA and RNA and hexose, hexosamine, and sialic acid in liver and kidney of treated rats were used to monitor the chemopreventive role of the plant extract. Remember me Forgot password?


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Chemical Constituents of Indigofera Aspalathoides Vahl. Ex. DC.

Chemotherapy, although being a major treatment modality used in the control of advanced stages of malignancies, exhibits severe toxicity on normal tissues [ 8 ]. In addition to a number of organic compounds metalssuch as nickel, lead, cadmium, cobalt and barium are also included in the category of carcinogens. Organic carcinogens acquire conversion to an ultimate more reactive compound.

The inorganic material was precipitated and filtered off. Changes in sialic acid content in serum lipoprotein fractions of cancer patients. The drug alone treated animals did not show aspalathodies marked variation as compared to normal control animals. In the stem and root, the crystals also occur in the ray parenchyma cells. Results During the entire period of our study no difference in food and water intake was observed among the groups of animals.

This could be due to the pain indigofea psychological stress on them due to the disease.