The GREACE study emphasizes the urgent need for a wider use of lipid-lowering drugs in high-risk patients. Evaluation (GREACE) Study consisted of patients with coronary heart disease (CHD) followed up for three years1. The patients were randomised to either. Our post-hoc analysis of the Greek Atorvastatin and Coronary Heart Disease Evaluation (GREACE) study was done to address this issue. Because of the.

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F does not store recipient email addresses. Statin treatment is safe and can improve liver tests and greqce cardiovascular morbidity in patients with mild-to-moderately abnormal liver tests that are potentially attributable to non-alcoholic fatty liver disease.

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The GREek Atorvastatin and Coronary-heart-disease Evaluation (GREACE) Study – UCL Discovery

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Long-term statin treatment reduces the frequency of cardiovascular events, but safety and efficacy in patients with abnormal liver tests is unclear. Long-term treatment of CHD patients with atorvastatin to achieve NCEP lipid targets significantly reduces total and coronary mortality, coronary morbidity and stroke, in comparison to patients receiving ‘usual’ medical care.

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User comments must be in English, comprehensible and relevant to the article under discussion. Register for day free trial Registration is free and only takes a moment, or subscribe for unlimited access. Withdrawal of patients because of side-effects from the atorvastatin group was low 0. Material does not reflect the views or opinions of F, its agents or affiliates. Certain parts of this website offer the opportunity for users to post opinions, information and material including without limitation academic papers and data ‘Material’ in areas of the website.

All subgroups of patients women, those with diabetes mellitus, arterial hypertension, age 60 to 75 years, congestive heart failure, recent unstable angina or prior revascularisation benefited from treatment with atorvastatin.

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UCL Discovery

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Secondary endpoints were the sfudy and efficacy of the hypolipidaemic drugs as well as the cost-effectiveness of atorvastatin. However, there is no long-term survival study that evaluated this statin. Primary endpoints of the study were defined as death, non-fatal myocardial infarction, unstable angina, congestive heart failure, revascularisation coronary morbidity and stroke.

This Agreement shall begin on the date hereof. These terms shall be governed by and construed in accordance with English Law. To assess the effect of atorvastatin on morbidity and mortality total and coronary of patients with established coronary heart disease CHDconsecutive patients were randomised either to atorvastatin or to ‘usual’ medical care.


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F reserves the right to remove any comments that it considers in its absolute discretion to be inappropriate, offensive or otherwise in breach sttudy the Terms and Conditions relating to Materials including Comments. You work at the same institute as any of the authors. In detail, atorvastatin reduced, in comparison to ‘usual’ care, total mortality RR 0.

GREACE (GREek Atorvastatin Coronary-heart-disease Evaluation) study – General Practice Notebook

Neither of the above. F does not claim any ownership in the Material that you or any other user posts. I am a Faculty Member who recommended this article. Recommend FPrime to your librarian or information manager to request an extended free trial for all users at your institution. Atorvastatin is very effective in reducing plasma low-density lipoprotein cholesterol LDL-C levels.

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All patients were followed up for a mean period of 3 years.