CASCADA DE COAGULACION INTRINSECA Y EXTRINSECA PDF

Los factores de la coagulación de la vía extrínseca se activan al producirse el La coagulación también puede activarse por la vía intrínseca al entrar en. El factor Xa desempeña un papel central en la cascada de coagulación debido a que ocupa un punto en el que convergen la vía intrínseca y la extrínseca. trabajo de cecilia lópez sampellegrini grado: enfermería. primer curso. asignatura: bioquímica, nutrición dietética. profesora: eva maría giner las enzimas su.

Author: Bragar Goltik
Country: Kuwait
Language: English (Spanish)
Genre: Career
Published (Last): 19 September 2012
Pages: 80
PDF File Size: 9.76 Mb
ePub File Size: 9.98 Mb
ISBN: 365-7-45626-907-5
Downloads: 81859
Price: Free* [*Free Regsitration Required]
Uploader: Mizuru

See examples translated by thrombin formation Noun 4 examples with alignment. An anticoagulant proteoglycan from the marine green alga, Codium pugni-formis. Cryptogamie Algolologie 16 3: Agardh, ChlorophytaLobophora variegata Lamoroux Womersley Phaeophyta and Liagora farinosa Lamouroux Rhodophyta were as potent as heparin impeding the clot formation in both thrombin and ce time tests.

The results showed other algae with slightly inhibition of clot formation activity, it is not common to consider this species for further investigation, nevertheless the retardation intrinsrca formation of clot by Penicillus capitatusa species evolutionary related to Halimeda genus Coagulaacion et al.

The samples for this study were manually collected from the seven localities described above, from the Gulf of Mexico and Mexican Caribbean sea during May to October figure etrinsecawere classified by genus and transported frozen to the laboratory using solid CO 2.

Anticoagulant activity in extracts of British marine algae. Agardh Rhodophyta retarded the coagulation process of human plasma in both anticoagulant tests for less than two minutes period and more than one minute.

A delay in clot formation less than two minutes was observed in prothrombin time test for this species from Chlorophyta: Se reporta por primera vez la actividad anticoagulante de Anadyomene stellataLobophora variegata y Liagora farinosa. Recently, a group of scientists had stand out the potentiality of some proteins and proteoglycans capable of interfere with blood clotting cascade, particularly coatulacion Codium Matsubara et al.

Translation of “formación de trombina” in English

Revista de la Sociedad Mexicana de Historia Natural Se concluye que estas especies pueden ser extrinzeca como una fuente alternativa de nuevos anticoagulantes. We can concluded that some substances present in the algal extract can act on any of the enzyme or substrate inhibiting the transformation of prothrombin to thrombin or in the activation process of fibrinogen to fibrin.

  ALPINE MRP-T220 PDF

Antihaemostatic activities of British marine algae. We considered an algal extract with anticoagulant activity similar to heparin when this impede the clot formation during 10 minutes or more. British Phycological Journal Screening for anticoagulant substances in some marine macroalgae. Current views on blood coagulation and haemostatic mechanism. It has been reported also that brown algae have a potent anticoagulant activity in fucoidans Chevolot et al.

Introduction to Applied Phycology. Introduction Thrombosis is a health problem that affects many people in the world. Bioscience Biotechnology and Biochemistry Remaining algal material was rinsed with tap water and distilled water.

CASCADA DE COAGULACION by mitzy sabrina rodriguez anaya on Prezi

Materials and methods The samples for this study were manually collected from the seven localities described above, from the Gulf of Mexico and Mexican Caribbean sea during May to October figure 1were classified by genus and transported frozen to the laboratory using solid CO 2. We considered that algal extracts have substances capable of inhibit clot formation in the last steps of the coagulation cascade.

Seasonal variations in the production of antifungal substances by some dictyotales brown algae from the French Mediterranean coast. These variation has been suggested as been influenced by geographical factors such as climate and locality and has been probed with primary metabolites as lectins by Ingram and Casfada et al.

Supporting the use of this method is the extrinssca that the results of Deacon et al. We also detected a variation in the anticoagulant potency, a change in the anticoagulant activity related with the intrinsic or extrinsic pathways of coagulation or even the disappearance of the anticoagulant activity in both test of Caulerpa cupressoidesC. We considered that extracts who acted on both path-ways of clot formation, affect the cascade of coagulation in the point of convergence, that is in transformation of fibrinogen to fibrin.

Caulerpa paspaloides Chlorophyta fue activa solamente en el tiempo de trombina. SPB Academic Publishing bv. Coagulaclon coagulation disorders have increased in the last decades and no new substances had been discovered that could regulate this illness.

  BIZU ODONTOLOGIA PDF

Results Results for algal extracts in both anticoagulant tests are in table 1. Journal Biological Chemistry A fibrinolytic enzyme from a marine green alga, Codium latum.

Seasonal variation of antibacterial and antifungal activities of the extracts of marine algae from southern coasts of India. It is not common that extracts from algae were active in both tests, in the literature are only few examples as Codium fragile subsp.

A total of five species were active in standard clotting test, three of Chlorophyta, one from Phaeophyta and one from Rhodophyta. We can suggest these four species as a sources of new anticoagulant substances.

Factor VIII – Viquipèdia, l’enciclopèdia lliure

Inhibition of Factor Xa interrupts the intrinsic and extrinsic pathway of the blood coagulation cascade, inhibiting both thrombin formation and development of thrombi. The discovery of alternative anticoagulant molecules must be an important task for scientists. The research effort has been focused on one genus, forgotten the basic detection of different algae as cscada potential source of alternative anticoagulant molecules.

In the central and eastern zones there are patches of sea-grass Halodule wrightiithe western part with algae. This last molecule is a sulfated glicosaminoglycan used in oral therapy for anticoagulant disorders.

Structure of a fucose-branched chondroitin sulfate from sea cucumber. This fact makes the discovery of new anticoagulant substances a priority issue in research. Biochimica et Biophysica Acta Finally, sample collected in April of change the anticoagulant activity been active only in the thrombin time test.

Factor VIII

American Journal of Clinical Pathology Occurrence of heparin in the invertebrate Styela plicata Tunicata is restricted to cell layers facing the outside environment. Comparative Biochemistry and Physiology B: On the quantitative estimation of coagulacoon. Purification and characterization of a fibrinolytic enzyme and identification of fibrinogen clotting enzyme in a marine green alga Codium divaricatum.

VPN