Bronchiolitis obliterans (BO), also known as popcorn lung and constrictive bronchiolitis, is a disease that results in obstruction of the smallest airways of the . Paziente con bronchiolite obliterante post-infettiva (sindrome di MacLeod). La scansione HRCT in inspirium (A) mostra un’ampia zona di oligoemia a mosaico. Request PDF on ResearchGate | Bronchiolite oblitérante postinfectieuse | Post- infectious bronchiolitis obliterans (BO) is characterized by inflammatory and.

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A lung biopsy is usually not necessary for diagnosis in the setting of classic symptoms, air trapping on imaging, airflow obstruction on spirometry in the setting of organ transplantation or toxic inhalational injury.

Bronchiolitis obliterans – Wikipedia

D ICD – Additional information Further information on this disease Classification s 1 Gene s 0 Other website s 1. Other symptoms that appear in obiterante workers include feverweight lossand night sweats.

Started inbroncjiolite collection now contains interlinked topic pages divided into a tree of 31 specialty books and chapters. Bronchiolitis obliterans BOalso known as popcorn lung and constrictive bronchiolitisis a disease that results in obstruction of the smallest airways of the lungs bronchioles due to inflammation.

Corticosteroidsimmunosuppressive medicationlung transplant [1] [4]. Spirometry showing obstructive pattern is necessary for diagnosis. Archived from the original on In non-transplant related bronchiolitis obliterans, removal from offending agents is essential.


It is a rare disease with characteristic features of fibrosis of terminal and distal bronchioles and spirometry showing airflow obstruction. Survival after bronchiolitis obliterans syndrome among bilateral lung transplant recipients. Bronchiolitis obliterans syndrome BOS is a lung disorder that is mainly associated with chronic allograft dysfunction after lung transplantation and that is characterized by inflammation and fibrosis of bronchiolar walls that reduce the diameter of the bronchioles and result in progressive and irreversible airflow obstruction.

Clinical symptoms include cough, dyspnea and influenza-like symptoms with the development of the usual interstitial pneumonia in many cases. Bronchus disorders Occupational diseases Industrial hygiene. Expert Rev Respir Med. Ann Am Thorac Soc. Lung volume tests may show hyperinflation excessive air in lungs caused by air trapping.

Chest radiographs may be normal in early disease or show signs of hyperinflation.

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Bronchiolitis obliterans is also known as obliterative bronchiolitis or constrictive bronchiolitis. In lung transplantation, microvascular insufficiency and alloimmune responses to the transplanted lung may result in airway injury and development of bronchiolitis obliterans syndrome.

The Occupational Safety and Health Administration OSHA recommended that diacetyl manufacturing companies regularly sample air in work environments, provide air purifying respirators, and engage in medical surveillance of at-risk workers.


Back Links pages that link to this page. A randomised controlled trial of azithromycin therapy in bronchiolitis obliterans syndrome BOS post lung transplantation.

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Bronchiolitis obliterans

Evaluation Pulmonary function testing is essential for diagnosis. Epidemiology Bronchiolitis obliterans syndrome is considered a form of chronic allograft rejection after lung transplantation.

History may also elicit recent exposure to toxic fumes or gases, viral infections, symptoms of joint stiffness in cases of rheumatoid arthritis, prior lung or hematopoietic stem cell transplantation. Am J Clin Pathology Symptoms do not change when workers are away from the workplace.

Orphanet: Bronchiolite obliterante avec trouble ventilatoire obstructif

Popcorn Lung Coming to Your Kitchen? For all other comments, please send your remarks via contact us.

Archived from the original on 17 December In other projects Wikimedia Commons. Chest XRay Variable appearance may be normal Bilateral ground glass, patchy appearance most common Diffuse nodular pattern.

Symptoms usually develop over weeks to months and are not episodic, unlike asthma.