extract of Glycyrrhiza glabra Linn. in aspirin induced ulcer in rats. . The aim of the study was to determine anti ulcer activity of stem bark of. Anti-ulcer activity was evaluated by measuring the ulcer index, gastric content, total Keywords: Anti-ulcer, Cold-restraint, Glycyrrhiza glabra, GutGardTM. The present research has been carried out to investigate antiulcer activity of ethanolic extract of Cynodon dactylon, Ocimum sanctum, Glycyrrhiza glabra, Ficus.

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The authors gratefully appreciate the financial support by the faculty of Veterinary Medicine Urmia University, Iran.

Anti Ulcer Activity Of Aloevera And Glycyrrhiza Glabra In Swiss Albino Rats |

Find articles by Ehsan Anassori. A possible anti-inflammatory and anti-ulcer drug. Oral treatment with indomethacin developed considerable glycyrrhizx in the glandular portion of stomach. Apart from flavonoids, the licorice also contains steroids such as beta sitosterol that is known to reduce the development of gastric ulcers 35 and glycyrrhizinic acid that possess gastric antiulcer properties Number of advantages are associated with use of herbal medicines as opposed to pharmaceutical products some of which include include reduced risk of side effects, effectives with chronic conditions, lower cost, widespread availability.

Glabridin is an isoflavonoid derivatives present in licorice. Increased macrophage glutathione content reduces cell-mediated oxidation of LDL and flycyrrhiza in apolipoprotein E-deficient mice.

Hypothermic restraint stress ulcer The experiment was performed by the method of Sairam et al. Flavonoids have shown cytoprotective activity in various models Although the etiology of gastric ulcers is still debated, it is accepted that ulcers are caused due to imbalances in mucosal aggressive and self-protective factors. Statistical analysis The experimental data were tested for statistical significance by means of analysis of variance with one-way classification.


Synthesis and anti-ulcer activity of new derivatives of glycyrrhetic,oleanolic and ursolic acids. Gastric and duodenal peptic ulcers affect thousands of people and in the clinical practice are the most common gastrointestinal disorders.

This model, cold restraint stress-induced gastric ulcers, has been used due to data reproducibility and similarity with human gastric ulcers to evaluate the effect of drugs on gastric secretion, stress and gastrointestinal motility.

In addition, some of these treatments may cause side effects like hypersensitivity, arrhythmia, weakness, and hematopoietic disorders 7. Researchers glabbra now focused on antiulcer agents that are less expensive, less toxic and very effective. The stomachs were removed and opened along the greater curvature. The anti-gastroulcerative activity of beta-sitosterol-beta-d-glucoside and its aglycone in rats.

Anti-ulcer activity of aqueous and ethanolic extracts of Glycyrrhiza glabra L. in rats.

Medicinal plants are among the most attractive source of new drugs with hopeful results in peptic ulcer management Find articles by Antiulccer Jalilzadeh-Amin. Ulcer index was calculated following the method described previously 9. Pharmaceutical Sciences Journals Ann Jose ankara escort.

Open in a separate window. The HEGG-induced gastroprotection in higher and lower doses were more effective. Nassiri M, Hosseinzadeh H.

He is a GPAT qualified student and presented oral and poster presentation in national antiulcerr seminars. Borrelli F, Izzo AA. Besides, being a popular food additive, licorice is also one of the most widely used medicinal herbs in Iran. The hydroalcoholic extract of G.


The plant kingdom as a source of antiulcer remedies. It seems that by raising the local concentration of prostaglandins that promote mucous secretion and cell proliferation in the stomach, leading to healing of ulcers in experimental studies The animals were kept under 12 h light-dark cycle and received water and commercial food ad libitum. Omeprazole also significantly inhibited the ethanol-induced gastric lesion The ulcer index was Consequently, the objective of the present study was to validate the antiulcer effect attributed to G.

The possibility of HEGG exerting a cytoprotective effect is gkabra because it successfully prevents the formation of gastric lesions in the indomethacin and ethanol induced ulcer models.

Recently it was shown that licorice in a combination product could heal ulcers effectively 33 that strongly confirm results of this study. The study was conducted using Omeprazole as the standard. Thereby it was reported, G.

However antiuulcer are very expensive and have multiple side effects that limit their usage. Omeprazole was most effective; it reduced the ulcer index to Extraction of Glycyrrhizic Acid and Glabridin from Licorice.

Hence, these constituents may be responsible for reduction of gastric ulcer indices and antiulcer effect of G. Aqueous extracts and polysaccharides from Liquorice roots Glycyrrhiza glabra L.