ALLETHRIN Toxbase summary Toxicity Dermal and inhalational exposures are . “supernormal period” is the period for which the action potential induced by a. They are not considered to cause delayed neurotoxicity of the kind induced by some organophosphorus compounds. The mechanism of toxicity of synthetic. Allethrin had 96 h LC50 toxicity values of µg/L, µg/L > µg/L, and .. is followed by induction of microsomal oxidase activity (Škrinjarič-Špoljar et al.

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Ultrastructural changes of tracheal epithelium and alveolar macrophages of rats exposed to mosquito-coil smoke. Under stress condition, p53 has been reported to activate pro-inflammatory cytokines at the site of stress induced pulmonary tissue in cigarette smoke inhaled rat [ 31 ].

Tumor necrosis factor-alpha overexpression in lung disease: Oxidative DNA damage with subsequent up-regulation of p53 is the perquisite of mitochondria mediated apoptosis [ 40 ]. Amelioration of Prallethrin-induced oxidative stress and hepatotoxicity in rat by the administration of Origanum majorana essential oil.

Allethrin toxicity causes reproductive dysfunction in male rats.

One MC, upon burning, produces such amount of particulate matter equivalent to that of 75— cigarettes [ 4 ]. Permethrin-induced oxidative stress and toxicity and metabolism. Results Biochemical study indicates elevated activity of two hepatic enzymes: MC generally has higher acceptance over liquid vaporizer due to its lower cost and ease of use.


Golla MadhubabuSuresh Yenugu Environmental toxicology The smoke is composed of two phases: Taken together, the biochemical parameters were altered by the inhalation with the mosquito coil smoke in a dose-dependent manner. Oxidative stress and hepatotoxicity induced by synthetic pyrethroids-organophosphate insecticides mixture in rat.

Pulmonary tissue of inhaled mice illustrates various degrees of histo-architectural changes in a doses dependent manner in comparison with that of allethtin Fig.

In this study, we found the biochemical and histological effects of the mosquito coil smoke using mice model. Mosquito coil, used in this study was purchased from local super market of Rajshahi by the trade name of Mortein power booster coil from Reckitt Benckiser, Bangladesh Ltd. Transverse section of lung of control mice shows normal and compact organization with thin intra-alveolar septa and alveolar sacs Fig.

Intact lung and liver were collected for histological analysis using standard protocol. Angireddy RajeshSuresh Yenugu Journal of reproductive immunology Received May 21; Accepted Aug Conceived designed and conducted the study as well as wrote the first draft of the manuscript. Microscopic observation of control liver shows regular and compact configuration with well-organized hepatocytes and central vein Fig.

Endocrine disrupting potential and reproductive dysfunction in male mice exposed to deltamethrin. Background Mosquito coil is the slow-burning structure made mainly of insecticides along with inert materials such as wood floor, coconut shell powder, starch etc.

Associated Data Data Availability Statement The datasets, supporting the conclusions of the results of this study are included within the article. Results from the present studies suggest that chronic exposure of allethrin based MC is responsible factor for severe health complications such as COPD due to the alterations of the key biochemical parameters of blood and histo-organization of lung and liver. Elastolytic metalloproteinases produced by human mononuclear phagocytes.


Biochemically, inhalation of the mosquito coil smoke altered dose dependently in all of the blood parameters tested. Mosquito coil emissions and health implications.

Sections were stained with hematoxylin and eosin Original magnification, X The interplay between apoptosis and necrosis may take place at the same time in the same tissue depending upon the types and degrees of death stimuli [ 42 ], which would also be supportive to the current dose dependent co-existence of apoptosis and necrosis in smoke inhaled tissues.

Allethrins (EHC 87, )

Exposure of pyrethrin based MC smoke has also been reported to considerable increase in white blood cell WBCespecially basophil and lymphocyte in rat [ 12 ]. Mosquito coil MC emits insecticide upon burning which provides limited protection against lethal mosquito borne diseases. Data indicates that the activity of two key hepatic enzymes i. The active ingredient of this brand was 0.

This study has some limitations relating to the conclusion of the results.